Salsalate Administration—A Potential Pharmacological Model of the Sick Euthyroid Syndrome

Sick euthyroid syndrome pdf

Review Article Euthyroid Sick Syndrome

Abnormalities in the circulating thyroid hormone concentration, without associated pituitary or thyroid disease, are seen in a variety of nonthyroidal illnesses (NIH). These abnormalities may be low plasma triiodothyronine (T3), low thyroxine (T4) or a combination of both, with an inappropriately normal plasma thyrotropin (TSH). These could be because of various factors acting on monodeiodinase...

A potential role of activated NF-κB in the pathogenesis of euthyroid sick syndrome

Thyroid hormone is one of the critical hormones in mammals and plays an indispensable role in development as well as in lipid and carbohydrate metabolism and energy generation. The thyroid gland secretes mainly L-thyroxine (T4) into the circulation where it is converted to 3,5,3′-triiodothyronine (T3) in liver and kidney. Most of the serum T3 is derived from this conversion, which is catalyzed ...

Changes in metabolism of TRH in euthyroid sick syndrome.

OBJECTIVE The aim of this study was to examine the metabolism of a simple dose, intravenously administered TRH bolus of 200 microg, in patients with euthyroid sick syndrome (ESS). PATIENTS AND METHODS A TRH test was performed on ten ESS patients and ten controls upon admission (d1) and after recovery (d2). Blood samples were collected at 0, 10, 20 and 30min after TRH injection. We analyzed th...

Euthyroid sick syndrome in children with diabetic ketoacidosis

OBJECTIVES To investigate characteristics of euthyroid sick syndrome (ESS) in children with diabetic ketoacidosis (DKA). METHODS This retrospective study was carried out between May 2010 and April 2013 at the Pediatric Department of Shandong Provincial Hospital, Shandong University, Shandong, China. Diabetic ketoacidosis children were divided into 2 groups: euthyroidism (group one, n=30) and ...