منابع مشابه
Ionomycin, a new polyether antibiotic.
Ionomycin, a new polyether antibiotic with a high affinity for calcium ions, is obtained in pure form from fermentation broths of Streptomyces conglobatus sp. nov. Trejo by solvent extraction. It is unique amongst known polyether antibiotics in that it has a UV absorption maximum at 300 nm. thereby distinguishing it from other antibiotics of its class. The Ca salt has the molecular formula C41H...
متن کاملIsolation of a new polyether antibiotic, lonomycin.
A new polyether antibiotic, lonomycin, was isolated from the culture of Streptomyces ribosidifcus strain TM-481. The antibiotic obtained as a sodium salt is a colorless prism having a molecular formula of C44H75O14Na(M.W. 850), m.p. 188 approximately 189 degrees C, and has no absorption maxima in the ultraviolet region. The infrared and NMR spectra of the antibiotic suggest the presence of a ca...
متن کاملEpigrisorixin, a new polyether carboxylic antibiotic.
addition of methyl oleate (1%) to the original fermentation culture increased the antibiotic titer3). Under these conditions, three nigericin-type antibiotics were isolated, grisorixin (1) (unpublished data), abierixin3) and epinigericin4) (3). The comparative biological activity of the two epimeric antibiotics, nigericin and epinigericin on a protist Tetrahymena pyriformis GL5) and Bacillus ce...
متن کاملCd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin
BACKGROUND The natural polyether ionophorous antibiotics are used for the treatment of coccidiosis in poultry and ruminants. They are effective agents against infections caused by Gram-positive microorganisms. On the other hand, it was found that some of these compounds selectively bind lead(II) ions in in vivo experiments, despite so far no Pb(II)-containing compounds of defined composition ha...
متن کاملStudies on a new polyether antibiotic, Ro 21-6150.
A new polyether antibiotic, Ro 21-6150, has been isolated from culture broths of Streptomyces hygroscopicus, strain X-14563. Ro 21-6150 has ionophore properties and is active in vitro against gram-positive bacteria.
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1974
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.27.814