Safety and Efficacy of Ambrisentan–Phosphodiesterase Type 5 (PDE5) Inhibitor Combination Therapy for Japanese Pulmonary Arterial Hypertension Patients in Real-World Clinical Practice

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منابع مشابه

Combination therapy with bosentan and phosphodiesterase-5 inhibitor in pulmonary arterial hypertension.

therapy to control lung damage in patients with common variable immunodeficiency. Int Immunopharmacol 2004; 6: 745–753. 4 de Gracia J, Morell F, Bofill JM, Rodrigo MJ, Cosculluela C. Impaired lung function in patients with IgA deficiency and low levels of IgG2 or IgG3. N Engl J Med 1986; 314: 925–926. 5 de Gracia J, Miravitlles M, Vendrell M, Rodrigo MJ, Codina R, Morell F. Study of the IgG sub...

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Dual phosphodiesterase type 5 inhibitor therapy for refractory pulmonary arterial hypertension: a pilot study

BACKGROUND Recent vasodilating drugs have improved prognosis of Pulmonary arterial hypertension (PAH). Some reports describe the merits of combination therapies for PAH, and this study evaluated the efficacy and safety of phosphodiesterase type 5 inhibitors (PDE5i) combination therapy, using sildenafil and tadalafil, for multi-drug-resistant PAH. METHODS We retrospectively analyzed 7 consecut...

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Goal-oriented treatment and combination therapy for pulmonary arterial hypertension.

Combination therapy may improve outcome in patients with severe pulmonary arterial hypertension (PAH). PAH patients were treated according to a goal-oriented therapeutic strategy. Patients who did not reach the treatment goals with monotherapy received combination treatment according to a predefined strategy, including bosentan, sildenafil and inhaled iloprost. Intravenous iloprost and lung tra...

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ژورنال

عنوان ژورنال: Circulation Reports

سال: 2019

ISSN: 2434-0790

DOI: 10.1253/circrep.cr-19-0029