Saccharomyces uvarum mannoproteins stimulate a humoral immune response in mice
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چکیده
منابع مشابه
Assessment of humoral immune response of a Cytomegalovirus DNA-vaccine candidate in BALB/c mice
Introduction: Glycoprotein B (gB) is the major antigen for induction of humoral responses against human cytomegalovirus (HCMV) making it an attractive candidate for immune prophylaxis. In the present study, the humoral immune response of BALB/c mice to a truncated HCMV gB protein fused with GFP was evaluated. Methods: The truncated gB coding sequence was synthesized and cloned in pEGFPN1 eukary...
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Background: Pseudomonas aeruginosa, an opportunistic pathogen, is a common cause of healthcare-associated infections in immunocompromised individuals. The rapid emergence of multidrug-resistant strains has made P. aeruginosa infections progressively difficult to treat. In this study we evaluated the effect of a chimeric protein containing a P. aeruginosa PilQ fragment and the PilA disulfide loo...
متن کاملThe Effect of Cationic Liposomes Encapsulating pcDNA3.1+PA Plasmids on Humoral Immune Response in Mice
Background: DNA vaccines are third generation vaccines which have made promises to combat infectious diseases. Cationic liposomes are used as effective delivery systems for DNA vaccines to generate stronger immunity. Objective: Encapsulation of pcDNA3.1+PA plasmid, encoding protective antigen (PA) of Bacillus anthracis (B. anthracis) into cationic liposomes, and evaluation of its effect on spec...
متن کاملMaturation of the Humoral Immune Response in Mice
In spite of the prenatal appearance of immunoglobulin-bearing lymphocytes and theta-positive lymphocytes in the spleens of Swiss-L mice, these mice are not able to produce detectable levels of humoral antibodies in response to antigen until after 1 wk of age. Adult levels of response are not achieved until 4-8 wk of age. In the presence of bacterial lipopolysaccharides, which can substitute for...
متن کاملassessment of humoral immune response of a cytomegalovirus dna-vaccine candidate in balb/c mice
introduction: glycoprotein b (gb) is the major antigen for induction of humoral responses against human cytomegalovirus (hcmv) making it an attractive candidate for immune prophylaxis. in the present study, the humoral immune response of balb/c mice to a truncated hcmv gb protein fused with gfp was evaluated. methods: the truncated gb coding sequence was synthesized and cloned in pegfpn1 eukary...
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ژورنال
عنوان ژورنال: Brazilian Archives of Biology and Technology
سال: 2012
ISSN: 1516-8913
DOI: 10.1590/s1516-89132012000400016