S9A-01 SESSION 9A

Electrochemical Synthesis, Structure Elucidation and Antibacterial Evaluation of 9a-aza-9a-chloro-9a- homoerythromycin A

Electrochemical synthesis, structure elucidation and antibacterial evaluation of 9a-aza-9a-chloro-9ahomoerythromycin A were carried out. It was found that the anodic oxidation of 9a-aza-9a-homoerythromycin A via electrogenerated reactive chlorine species leads to the chlorination of lactam nitrogen in high yield provided the pH of the reaction mixture is maintained above 3. NOESY spectra reveal...

9-phenyl-3,4,4a,9a-tetrahydrotriptycene and 9-phenyl-1,2,3,4,4a,9a-hexahydrotriptycene

Poster Session 01: Reproductive physio-pharmacology and new agents

Acertain number of plant exteracts are known to stimulate milksecretion in lactaiting women .These extracts injected intravenously to Eweor administered orally induced a marked secretion of Prolactin. Thecompound which proved to be active in the plant exteracts wasPectin.Pectic acid which stimulates Prolactin release in vivo were added.Tothe culture mediumof the GH3/B6 rat p...

rac-7,7′,9,9′-Tetra­phenyl-9a,9a′-bi(7,8,9,9a-tetra­hydro-6aH-penta­leno[1,2,3-ij]naphthalen-8-one)

The racemic title compound, C(54)H(38)O(2), consists of two C-linked penta-leno[1,2,3-ij]naphthalenone moieties, the crowded aryl ring substitution on the cyclo-pentane rings forcing the two segments to assume a conformation which has pseudo-twofold rotational symmetry, with a dihedral angle between the naphthalene substituent groups of 55.30 (8)°. In each segment, the two phenyl rings have dif...

Frequencies of HLA-E*01:01/*01:03 Alleles in an Iranian Healthy Population and Its Comparison with Hyperglycemia Patients

Background and Aims: The human leukocyte antigen-E (HLA-E) is a member of non-classical HLA class-I genes which is highly conserved through evolution. In general, so far 25 alleles of HLA-E have been described. However, the existence of only two allelic group; HLA-E*01:01 and HLA-E*01:03 have been demonstrated in all the populations. HLA-E*01:01 and HLA-E*01:03 differ only at codon 107 of exon ...