S55 Neural Respiratory Drive Using Parasternal Electromyography In Clinically Stable Cystic Fibrosis Patients: A Physiological Marker Of Lung Disease Severity And Exercise Capacity
نویسندگان
چکیده
منابع مشابه
Physiological markers of exercise capacity and lung disease severity in cystic fibrosis.
BACKGROUND AND OBJECTIVE Peak aerobic capacity (VO2 peak) is an important outcome measure in cystic fibrosis (CF), but measurement is not widely available and can be influenced by patient motivation, pain and fatigue. Alternative markers of disease severity would be helpful. Neural respiratory drive, measured using parasternal intercostal muscle electromyography (EMGpara), reflects the load to ...
متن کاملMaintaining Respiratory Health in Cystic Fibrosis Patients
Cystic fibrosis (CF) is an inherited disease that primarily affects the lungs and the digestive system, however, it also affects a number of other organs and systems. More than 90% of mortality of CF patients is due to lung complications. Healthy lungs are important for a long life for people with CF, We will discuss two important topics for maintaining respiratory health. Chronic use of drug...
متن کاملMonitoring respiratory disease severity in cystic fibrosis.
Measurements of disease severity provide a guide for the physician to tailor therapies, for the patient and family to gauge progress, and are required for clinical trials. For many respiratory diseases, including cystic fibrosis, sensitive, noninvasive measurements are few, and some of those that are available are applicable only to certain subgroups of patients or lack sufficient sensitivity. ...
متن کاملMeasurement of neural respiratory drive via parasternal intercostal electromyography in healthy adult subjects.
Neural respiratory drive, quantified by the parasternal intercostal muscle electromyogram (EMGpara), provides a sensitive measure of respiratory system load-capacity balance. Reference values for EMGpara-based measures are lacking and the influence of individual anthropometric characteristics is not known. EMGpara is conventionally expressed as a percentage of that obtained during a maximal ins...
متن کاملDeterminants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease
BACKGROUND Adult patients with cystic fibrosis (CF) frequently have reduced exercise tolerance, which is multifactorial but mainly due to bronchial obstruction. The aim of this retrospective analysis was to determine the mechanisms responsible for exercise intolerance in patients with mild-to-moderate or severe disease. METHODS Cardiopulmonary exercise testing with blood gas analysis at peak ...
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ژورنال
عنوان ژورنال: Thorax
سال: 2014
ISSN: 0040-6376
DOI: 10.1136/thoraxjnl-2014-206260.61