S10 Cost Burden Of N-acetylcysteine (nac) In Adult Patients With Idiopathic Pulmonary Fibrosis

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Efficacy of N-Acetylcysteine in Idiopathic Pulmonary Fibrosis

There are a number of conflicting reports describing the clinical outcomes of using N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis. We have, therefore, performed a meta-analysis to evaluate the efficacy of N-acetylcysteine, compared with control, for the treatment of idiopathic pulmonary fibrosis.Original controlled clinical trials evaluating the efficacy of N-acetylcystein...

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The Point on N-acetylcysteine in Idiopathic Pulmonary Fibrosis Treatment

Idiopathic pulmonary fibrosis (IPF) is still a non-curable disease. The suggested therapy consists of Pirfenidone combined with other drugs like azathioprine, and acetylcysteine. The New England Journal of Medicine published a new study that goes against the common use of N-acetylcysteine (NAC) to treat IPF patient. There are other studies that went in favor of N-acetylcysteine. The present stu...

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The Point on N-acetylcysteine in Idiopathic Pulmonary Fibrosis Treatment

Idiopathic pulmonary fibrosis (IPF) is still a non-curable disease. The suggested therapy consists of Pirfenidone combined with other drugs like azathioprine, and acetylcysteine. The New England Journal of Medicine published a new study that goes against the common use of N-acetylcysteine (NAC) to treat IPF patient. There are other studies that went in favor of N-acetylcysteine. The present stu...

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Long-term efficacy of inhaled N-acetylcysteine in patients with idiopathic pulmonary fibrosis.

BACKGROUND Inhalation of N-acetylcysteine (NAC) has been carried out in our department since 1994 for treating interstitial pneumonia such as idiopathic pulmonary fibrosis (IPF). In this study, the clinical efficacy and safety of long-term NAC inhalation monotherapy for IPF was investigated. METHODS NAC inhalation was carried out in 23 of 34 cases diagnosed as IPF by surgical lung biopsy in o...

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High-dose acetylcysteine in idiopathic pulmonary fibrosis.

BACKGROUND Idiopathic pulmonary fibrosis is a chronic progressive disorder with a poor prognosis. METHODS We conducted a double-blind, randomized, placebo-controlled multicenter study that assessed the effectiveness over one year of a high oral dose of acetylcysteine (600 mg three times daily) added to standard therapy with prednisone plus azathioprine. The primary end points were changes bet...

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ژورنال

عنوان ژورنال: Thorax

سال: 2014

ISSN: 0040-6376

DOI: 10.1136/thoraxjnl-2014-206260.16