S-Alkylated/aralkylated 2-(1H-indol-3-yl-methyl)-1,3,4- oxadiazole-5-thiol derivatives. 2. Anti-bacterial, enzymeinhibitory and hemolytic activities
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منابع مشابه
Methyl 2-(5-fluoro-1H-indol-3-yl)-2-oxoacetate
The indolyl portion of the title mol-ecule, C(11)H(8)FNO(3), is flat, the five- and six-membered rings making a dihedral angle of 0.815 (6)°. Inter-molecular N-H⋯O hydrogen bonds link adjacent mol-ecules into a linear chain. Slipped π-π stacking inter-actions between two neighboring indole groups further consolidate the mol-ecules into a three-dimensional supra-molecular architecture [centroid-...
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In the title compound, C22H14ClN3O2, the indole unit is essentially coplanar, with a maximum deviation of 0.035 Å for the C atom bearing the methyl group. The central pyridine ring is inclined to the indole ring system by 43.7 (1)°. The dihedral angle between the phenyl ring and the indole ring system is 15.7 (2)°, while that between the phenyl ring and the central pyridine ring is 46.3 (1)°. T...
متن کامل2-[5-Bromo-1-(3-chlorobenzyl)-2-methyl-1H-indol-3-yl]acetic acid
In the title compound, C18H15BrClNO2, the indole ring system forms a dihedral angle of 86.9 (2)° with the 3-chloro-benzyl ring. In the crystal, mol-ecules form inversion dimers connected via pairs of O-H⋯O hydrogen bonds.
متن کامل(2-Methyl-1-phenylsulfonyl-1H-indol-3-yl)phenylmethyl acetate
In the title compound, C(24)H(21)NO(4)S, the indole ring system makes dihedral angles of 77.8 (1) and 85.4 (1)°, respectively, with the S- and C-bound phenyl rings. The mol-ecular structure is stabilized by a weak intra-molecular C-H⋯O hydrogen bond. In the crystal, a weak inter-molecular C-H⋯O hydrogen bond and a C-H⋯π inter-action are also observed.
متن کامل(2-Methyl-1-phenylsulfonyl-1H-indol-3-yl)methanol
In the title compound, C(16)H(15)NO(3)S, the plane of the phenyl ring forms a dihedral angle of 80.37 (8)° with the indole ring system. The crystal packing is stabilized by weak O-H⋯O hydrogen bonds which link the mol-ecules into infinite chains along the a axis of the crystal.
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2016
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v15i7.24