Rotator Cuff Repair Augmentation Using Osteoinductive Growth Factors

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Biologic augmentation of rotator cuff tendon-healing with use of a mixture of osteoinductive growth factors.

BACKGROUND Clinical studies have demonstrated a high rate of incomplete healing of rotator cuff tendon repair. Since healing of such a repair is dependent on bone ingrowth into the repaired tendon, we hypothesized that osteoinductive growth factors would improve rotator cuff tendon-healing. METHODS Seventy-two skeletally mature sheep underwent detachment of the infraspinatus tendon followed b...

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Growth factors for rotator cuff repair.

The 4 fibrocartilagenous transition zones of the rotator cuff insertion site are not recreated following surgical repair. Instead, a layer of scar tissue is formed between the tendon and the bone, which makes repairs prone to failure. Growth factors are a group of cytokines that induce mitosis, extracellular matrix production, neovascularization, cell maturation, and differentiation. Research h...

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Augmentation techniques for rotator cuff repair.

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Arthroscopic bone tunnel augmentation for rotator cuff repair.

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ژورنال

عنوان ژورنال: SN Comprehensive Clinical Medicine

سال: 2019

ISSN: 2523-8973

DOI: 10.1007/s42399-019-0041-z