Rooting Gene Trees without Outgroups: EP Rooting

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Rooting Gene Trees without Outgroups: EP Rooting

Gene sequences are routinely used to determine the topologies of unrooted phylogenetic trees, but many of the most important questions in evolution require knowing both the topologies and the roots of trees. However, general algorithms for calculating rooted trees from gene and genomic sequences in the absence of gene paralogs are few. Using the principles of evolutionary parsimony (EP) (Lake J...

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Rooting phylogenies is critical for understanding evolution, yet the importance, intricacies and difficulties of rooting are often overlooked. For rooting, polymorphic characters among the group of interest (ingroup) must be compared to those of a relative (outgroup) that diverged before the last common ancestor (LCA) of the ingroup. Problems arise if an outgroup does not exist, is unknown, or ...

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ژورنال

عنوان ژورنال: Genome Biology and Evolution

سال: 2012

ISSN: 1759-6653

DOI: 10.1093/gbe/evs047