Roles and practice of living-related lobar lung transplantation
نویسندگان
چکیده
: Living-donor lobar lung transplantation (LDLLT) was first performed in the USA and thereafter it introduced Japan 1998 as an alternative modality to brain-dead donor (BDLT). Although LDLLT procedure employed for rapidly deteriorating patients who were hospitalized mechanically ventilated at time of transplantation, demonstrated better or comparable post-transplant outcomes comparison BDLT. Less injured grafts a significantly shorter graft ischemic possibly contributed lower incidence severe primary dysfunction (PGD) after In standard LDLLT, obtained from two different donors, thus most developed chronic allograft (CLAD) only unilateral graft. This indicates that contralateral unaffected could reserve function development CLAD. our transplant program, CLAD per (14.4%) also BDLT (24.7%). The 1-, 5- 10-year survival rates 90.9%, 75.5% 57.2%, respectively, which equivalent those (92.9%, 73.4% 62.2%). inherent surgical risk living donors should always be considered. experience, living-donor surgery associated with complication rate 12.7%, importantly, all finally returned their previous social lives. Precise functional anatomical size matching between recipient provide favorable pulmonary LDLLT. We recently established multimodal approaches, such native upper lobe-sparing, right-to-left horizontally rotated, segmental, single-lobe order resolve issue mismatch recipient.
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OBJECTIVES Living-donor lobar lung transplantation (LDLLT) has been established as a life-saving procedure for critically ill patients who cannot wait for cadaveric lung transplantation. Chronic lung allograft dysfunction (CLAD) is the main cause of late morbidity and mortality in lung transplantation. Studies on CLAD in cadaveric lung transplantation have been extensively reported, but few rep...
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ژورنال
عنوان ژورنال: Journal of Thoracic Disease
سال: 2023
ISSN: ['2077-6624', '2072-1439']
DOI: https://doi.org/10.21037/jtd-22-1867