Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line
نویسندگان
چکیده
منابع مشابه
Anti-Müllerian hormone: a potentially useful biomarker for the diagnosis of canine Sertoli cell tumours
BACKGROUND Testicular tumours are common in dogs and in many cases do not give rise to clinical signs. In other cases, signs of feminization, hyperpigmentation or alopecia may be observed, most commonly associated with Sertoli cell tumours (SCT). Although these signs are often associated with elevated concentrations of oestradiol, analysis of oestradiol may give inconclusive results due to larg...
متن کاملHormonal and cellular regulation of Sertoli cell anti-Müllerian hormone production in the postnatal mouse.
Anti-Müllerian hormone (AMH) is secreted by immature testicular Sertoli cells. Clinical studies have demonstrated a negative correlation between serum AMH and testosterone in puberty but not in the neonatal period. We investigated AMH regulation using mouse models mimicking physiopathological situations observed in humans. In normal mice, intratesticular, not serum, testosterone repressed AMH s...
متن کاملAnti-müllerian hormone and sertoli cell function in paediatric male hypogonadism.
In the prepubertal male, Sertoli cells are the most active testicular cell population. Without stimulation tests, prepubertal hypogonadism can only be evidenced if Sertoli cell function is assessed. Anti-müllerian hormone (AMH) is a distinctive marker of the prepubertal Sertoli cell. Serum AMH is high from fetal life until puberty. In postnatal life, AMH testicular production is stimulated by F...
متن کاملAnti - Müllerian hormone in sheep follicles ( 1 )
The purpose of this work was to study anti-MOllerian hormone (AMH) secretion during ovarian development in sheep before and after birth. We used avidinbiotin immunocytochemistry and a monoclonal antibody specific for ruminant AMH. Only granulosa cells have an immunoreactivity ; this immunoreactivity was influenced by animal age and by the degree of follicular development. In the fetus, no immun...
متن کاملRegulation of ovarian function: the role of anti-Müllerian hormone.
Anti-Müllerian hormone (AMH), also known as Müllerian inhibiting substance, is a member of the transforming growth factor beta superfamily of growth and differentiation factors. In contrast to other members of the family, which exert a broad range of functions in multiple tissues, the principal function of AMH is to induce regression of the Müllerian ducts during male sex differentiation. Howev...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2005
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1208686