Role of Purinergic Signaling in Voiding Dysfunction
نویسندگان
چکیده
منابع مشابه
Voiding Dysfunction in Childhood
Urologists are often asked to attend a child with wetting or voiding problems. These are the more common paediatric conditions seen in a urology clinic. The child may have enuresis, voiding frequency or incontinence. Although a majority of these cases run a benign course, it is necessary to differentiate them from others that may develop into serious complication, namely upper urinary tract dam...
متن کاملVoiding dysfunction in children.
The practicing urologist commonly sees children with lower-urinary tract dysfunction who wet or have recurrent urinary tract infections. This article identifies the proposed etiologies of such behavior in children in whom there are no anatomic or neuropathic causes, outlines the approach to evaluating affected children, and describes a stepwise,interdisciplinary approach to treatment.
متن کاملVoiding dysfunction: definitions.
'Lower urinary tract symptoms' is a term that describes symptoms related to both the storage and emptying phases of the micturition cycle. Storage symptoms include urinary frequency urgency, urge incontinence, nocturia, dysuria and other kinds of pain emanating from the bladder or urethra. Emptying symptoms consist of hesitancy, straining to void, difficulty starting, diminished stream, a feeli...
متن کاملVoiding Dysfunction in Multiple Sclerosis
Objective: To determine the relationships between urological features of multiple sclerosis (MS) and various disease parameters. Material and Methods: Forty-three patients with MS were evaluated. Urinary complaints, disease duration, urologic symptom duration, time elapsed till urologic symptom, expanded disability status score (EDSS), and bladder functional score (BFS) for each patient were co...
متن کاملRole of purinergic signaling in experimental pneumococcal meningitis
Excessive neutrophilic inflammation contributes to brain pathology and adverse outcome in pneumococcal meningitis (PM). Recently, we identified the NLRP3 inflammasome/interleukin (IL)-1β pathway as a key driver of inflammation in PM. A critical membrane receptor for NLRP3 inflammasome activation is the ATP-activated P2 purinoceptor (P2R) P2X7. Thus, we hypothesized involvement of ATP and P2Rs i...
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ژورنال
عنوان ژورنال: Current Bladder Dysfunction Reports
سال: 2010
ISSN: 1931-7212,1931-7220
DOI: 10.1007/s11884-010-0063-6