Role Of Copper For Human Organism
نویسندگان
چکیده
منابع مشابه
Copper in the Human Organism
Copper is an essential micronutrient for human bodies, whose distribution in different organs and tissues, metabolism and physiological impact is not thoroughly explained yet. Further issues which need clarification are the exact composition and constitution of its combinations with other elements, the physiological impact of copper and copper-enzymes in sickness and health. Biomarkers for iden...
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The aim of this study was to design and optimize a new tablet formulation for treatment of copper deficiency in human organism by using an experimental design. The new no-veneered tablets, prepared by a wet granulation technique, are containg active substance, a copper(II) complex with polysaccharide pullulan. The binder concentration, the disintegrant concentration and the resistance to crushi...
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Copper is a trace element present in all tissues and is required for cellular respiration, peptide amidation, neurotransmitter biosynthesis, pigment formation, and connective tissue strength. Copper is a cofactor for numerous enzymes and plays an important role in central nervous system development; low concentrations of copper may result in incomplete development, whereas excess copper maybe i...
متن کاملRole of copper transporters in copper homeostasis.
Copper is a redox active metal that is essential for biological function. Copper is potentially toxic; thus, its homeostasis is carefully regulated through a system of protein transporters. Copper is taken up across the lumen surface of the small intestinal microvilli as cuprous ion by Ctr1. Cupric ion may also be taken up, but those processes are less well understood. Within the cell, intestin...
متن کاملCellular glutathione plays a key role in copper uptake mediated by human copper transporter 1 Edward
Maryon EB, Molloy SA, Kaplan JH. Cellular glutathione plays a key role in copper uptake mediated by human copper transporter 1. Am J Physiol Cell Physiol 304: C768–C779, 2013. First published February 20, 2013; doi:10.1152/ajpcell.00417.2012.—Copper is an essential micronutrient. Following entry via the human copper transporter 1 (hCTR1), copper is delivered to several copper chaperones, which ...
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ژورنال
عنوان ژورنال: European Medical, Health and Pharmaceutical Journal
سال: 2011
ISSN: 1804-9702,1804-5804
DOI: 10.12955/emhpj.v2i0.336