RNAIndel: discovering somatic coding indels from tumor RNA-Seq data
نویسندگان
چکیده
منابع مشابه
Investigating the Function of Predicted Proteins from RNA-Seq Data in Holstein and Cholistani Cattle Breeds
This study was performed to determine the digital expression profile of different genes expressed in Holstein and Cholistani breeds as well as to evaluate the performance of predicted proteins derived from differentially expressed genes between these two breeds using RNA-Seq data. For this purpose, the whole mRNA sequence for a blood sample of American Holstein and Pakistani Cholistani cattle p...
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MOTIVATION A new protocol for sequencing the messenger RNA in a cell, known as RNA-Seq, generates millions of short sequence fragments in a single run. These fragments, or 'reads', can be used to measure levels of gene expression and to identify novel splice variants of genes. However, current software for aligning RNA-Seq data to a genome relies on known splice junctions and cannot identify no...
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As a revolutionary way to unveil transcription, RNA-Seq technologies are challenging bioinformatics for its large data volumes and complexities. A large number of computational models have been proposed for differential expression (DE) analysis and normalization from different standing points. However, there were no studies available yet to conduct disease biomarker discovery for this type of h...
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The TBX20 data set [4] provides ChIP-Seq and RNA-Seq data. In here only the RNA-Seq part of the data is utilized. The raw data where downloaded from Gene Expression Omnibus (GEO) [1], accession number GSM767225GSM767230. TBX20 (T-box 20) in general is a transcriptional regulator essential for cardiac development and maintenance of mouse heart tissue. In this study TXB20 was knocked-out by using...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2020
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btaa247