منابع مشابه
RNAi technology: A Novel approaches against fungal infections
Despite the introduction of new antifungal agents, resistances to antifungal therapy continue to increase and outcome of invasive fungal infections treatment is frequently suboptimal. A large amount of the recent effort in antifungal drug discovery has focused on a limited set of targets with functions known or expected to be important for fungal viability and virulence. A variety of techniques...
متن کاملVirus meets RNAi
Introduction Small rnas are important regulators of gene expression that operate through a range of rna-silencing mechanisms. of these, rna interference (rnai)—gene silencing through small-interfering rnas (sirnas) derived from exogenous double-stranded rna (dsrna)—and the microrna (mirna) pathway—gene silencing guided by small rnas encoded in the genome—are the best known. the discovery that d...
متن کاملNora Virus Persistent Infections Are Not Affected by the RNAi Machinery
Drosophila melanogaster is widely used to decipher the innate immune system in response to various pathogens. The innate immune response towards persistent virus infections is among the least studied in this model system. We recently discovered a picorna-like virus, the Nora virus which gives rise to persistent and essentially symptom-free infections in Drosophila melanogaster. Here, we have us...
متن کاملTzanck smears in herpes simplex virus infections
Background: The diagnosis of herpes simplex virus may requirevirological confirmation. Tzanck smear is an old, rapid, costeffective but nonspecific method that has been recently re-evaluatedas a method for the diagnosis of herpes virus infection. This studywas conducted to compare Tzanck smear and viral culture in thediagnosis of herpes simplex virus infection in patients clinicallysuspected to...
متن کاملrnai technology: a novel approaches against fungal infections
despite the introduction of new antifungal agents, resistances to antifungal therapy continue to increase and outcome of invasive fungal infections treatment is frequently suboptimal. a large amount of the recent effort in antifungal drug discovery has focused on a limited set of targets with functions known or expected to be important for fungal viability and virulence. a variety of techniques...
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ژورنال
عنوان ژورنال: Microbe Magazine
سال: 2007
ISSN: 1558-7452,1558-7460
DOI: 10.1128/microbe.2.296.1