منابع مشابه
RNA 3D structure prediction: (1) assessing rna 3D structure similarity from 2D structure similarity.
Computational techniques for 3D structure prediction of proteins, the holy grail of bioinformatics, have undergone major developments in recent years, geared by international cooperation and competition with CASP (Critical Assessment of Structure Prediction Techniques) like contests to improve and refine them. Although straightforward extrapolation of these methodologies for the prediction of t...
متن کامل3D Structure from 2D Motion
In their day-to-day lives, people naturally understand and operate in a three dimensional world. Curiously, though, they only sense 2D projections of it. The seemingly e ortless act of inferring 3D from 2D observations is the result of complex mechanisms that are still quite far from being resolved. For many years, this task has been considered the primary role of visual processing. Pioneers in...
متن کاملTowards de novo RNA 3D structure prediction
RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes within the cell. Computational algorithms can be of great help in the understanding of RNA structure-function relationship. One of the main challenges in this field is the development of structure-prediction algorithms, which aim at the prediction of the three-dimensional (3D) native fold from the sol...
متن کاملProtein Structure Prediction in 1D, 2D, and 3D
Abbreviations 1D D one-dimensional; 1D structure D one-dimensional (e.g., sequence or string of secondary structure); 2D D two-dimensional; 2D structure D two-dimensional (e.g., interresidue distances); 3D D three-dimensional; 3D structure D three-dimensional (coordinates of protein structure); PDB D Protein Data Bank of experimentally determined 3D structures of proteins; SWISS-PROT D database...
متن کاملRNA-MoIP: prediction of RNA secondary structure and local 3D motifs from sequence data
RNA structures are hierarchically organized. The secondary structure is articulated around sophisticated local three-dimensional (3D) motifs shaping the full 3D architecture of the molecule. Recent contributions have identified and organized recurrent local 3D motifs, but applications of this knowledge for predictive purposes is still in its infancy. We recently developed a computational framew...
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ژورنال
عنوان ژورنال: Emerging Topics in Life Sciences
سال: 2017
ISSN: 2397-8554,2397-8562
DOI: 10.1042/etls20160027