منابع مشابه
RNA silencing
RNA silencing is a newly discovered mechanism of genetic regulation in eukaryotes. It is based on an immune system that protects eukaryotes against viruses and transposons and in some respects it is conceptually similar to classical humoral immunity. However RNA silencing is distinct from humoral immunity in that it only targets nucleic acids and has a specificity mechanism based on nucleic aci...
متن کاملRNA silencing in Monterey.
The tenth annual Keystone Symposium on the Mechanism and Biology of Silencing convened in Monterey, California, in March 2011. Those seeking some West Coast sunshine were, unfortunately, met with incessant precipitation throughout the meeting. Nevertheless, attendees were brightened by enlightening and vigorous scientific discussions. Here, we summarize the results presented at the meeting, whi...
متن کاملRNA-triggered gene silencing.
Double-stranded RNA (dsRNA) has recently been shown to trigger sequence-specific gene silencing in a wide variety of organisms, including nematodes, plants, trypanosomes, fruit flies and planaria; meanwhile an as yet uncharacterized RNA trigger has been shown to induce DNA methylation in several different plant systems. In addition to providing a surprisingly effective set of tools to interfere...
متن کاملRNA silencing in Drosophila.
Knowledge of the role of RNA in affecting gene expression has expanded in the past several years. Small RNAs serve as homology guides to target messenger RNAs for destruction at the post-transcriptional level in the experimental technique known as RNA interference and in the silencing of some transgenes. These small RNAs are also involved in sequence-specific targeting of chromatin modification...
متن کاملایجاد گیاه سیب زمینی مقاوم به ویروس PVX با استفاده از مکانیسم RNA Silencing
یکی از عوامل اصلی کاهش محصول سیب زمینی ویروسها هستند. ویروس X سیب زمینی (Potato X Potexvirus: PVX) از مهمترین ویروسهای این گیاه میباشد و عمده ترین روش مبارزه با آن استفاده از ارقام مقاوم است. در این تحقیق سعی شد با بهره گیری از تکنیک RNA silencing گیاهان سیب زمینی مقاوم به این ویروس تولید شود. برای اینکار ابتدا با دو همسانه سازی متوالی یک سازه سنجاقسری برای انتهای ژن P25 ویروس PVX در ن...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2002
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)00665-6