RNA interference-based therapeutics for shrimp viral diseases
نویسندگان
چکیده
منابع مشابه
Antisense antivirals: future oligonucleotides-based therapeutics for viral infectious diseases
Despite the availability of antiviral chemotherapies, human pathogenic viral infections remain a global health problem, causing formidable morbidity and mortality worldwide. Of particular concern are those virus types developing (multi)drug-resistance, eg. herpesviruses, hepatitis C virus (HCV), and human immunodeficiency virus (HIV), that fail almost all the available antiviral drugs in clinic...
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The treatment of viral infections has relied on pre-emptive vaccination or use of a limited range of anti-viral drugs. However, the majority of viruses have no available drugs and treatment is merely supportive. RNA interference (RNAi) offers the ability to directly and rapidly treat virus infections via the targeting of viral genes. Indeed, clinical trials have already been undertaken with pro...
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The central dogma of biology describes the transfer of biological information from DNA through to protein (Crick, 1970). In the first phase, known as transcription, DNA is converted into a complementary sequence of messenger RNA (mRNA). This mRNA allows the genetic message to be communicated outside of the nucleus, to other areas of the cell, where it is then translated into protein by ribosome...
متن کاملEmerging viral diseases of fish and shrimp
The rise of aquaculture has been one of the most profound changes in global food production of the past 100 years. Driven by population growth, rising demand for seafood and a levelling of production from capture fisheries, the practice of farming aquatic animals has expanded rapidly to become a major global industry. Aquaculture is now integral to the economies of many countries. It has provid...
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ژورنال
عنوان ژورنال: Diseases of Aquatic Organisms
سال: 2009
ISSN: 0177-5103,1616-1580
DOI: 10.3354/dao02126