Risk of second malignancies after definitive therapy for esophageal cancer: A competing risk analysis

Second cancer risk after interferon therapy?

Risk of second primary cancer among esophageal cancer patients: a pooled analysis of 13 cancer registries.

BACKGROUND The objective of this study is to assess the risk of second primary cancers following a first primary esophageal cancer as well as the risk of esophageal cancer as a second primary, following first primary cancers of other sites. METHODS The present investigation is a multicenter study of 13 population-based cancer registries in Europe, Australia, Canada, and Singapore. To assess e...

Androgen deprivation therapy for treatment of localized prostate cancer and risk of second primary malignancies.

BACKGROUND While androgen deprivation therapy (ADT) is a common treatment for prostate cancer, little is known regarding its long-term health effects, particularly as it relates to the development of second primary malignancies. Therefore, the goal of this study was to assess the association between ADT use and second primary malignancies among men diagnosed with localized prostate cancer. ME...

Clinicopathological examination of ESD as salvage therapy for esophageal cancer after definitive chemo-radiation therapy

Background and study aims  Salvage therapy for esophageal cancer following chemo-radiation therapy (CRT) has not been established. We aimed to evaluate endoscopic submucosal dissection (ESD) as a salvage therapy based on histopathological features of lesions. Patients and methods  We compared 10 lesions in eight patients with local residual, recurrent, or metachronous esophageal squamous cell...

Alcohol abstinence and risk assessment for second esophageal cancer in Japanese men after mucosectomy for early esophageal cancer

BACKGROUND Alcohol consumption combined with inactive aldehyde dehydrogenase-2 (ALDH2) and the presence of multiple esophageal Lugol-voiding lesions (LVLs; dysplasia) are strong predictors for multiple development of esophageal squamous cell carcinoma (ESCC) in East Asians. We invented a health risk appraisal (HRA) model for predicting the risk of ESCC based on drinking, smoking, dietary habits...