Risk Factors of Acute and Chronic Erythema Nodosum Leprosum in Dr. Soetomo General Academic Hospital Surabaya
نویسندگان
چکیده
Background: Leprosy is a chronic granulomatous infection and one of the neglected diseases caused by Mycobacterium leprae. ENL complex syndrome, that inflammation skin, nerves, other organs due to an inflammatory immune response leprae antigens. Acute was defined as first episode with duration less than 24 weeks. Chronic persisted for more These types can have different risk factors require therapeutic interventions. Purpose: The onset acute, but may progress or recurrent phase long-term therapy. Early detection leprosy very important, because curable prompt treatment reduce nerve damage associated stigma. patients prolonged high doses corticosteroids control in cause severe complications side effects morbidity mortality. Methods: This retrospective study conducted using non-probability sampling technique consecutively casecontrol formula Division Outpatient Dermatology Venereology Unit RSUD Dr. Soetomo Surabaya period 2015 – 2020, secondary data form medical record data. Result: results this obtained many 234 patients, 56 acute 89 ENL. 45 were from case-control minimal sample size formula. Conclusion: bivariate analysis test showed there relationship between coinfection steroid therapy type presence tend be ENL, conversely, absence without therapy, multivariate logistic regression significant association before MDT whereas after
منابع مشابه
Risk Factors of Vulvovaginal Candidiasis in Dermato-venereology Outpatients Clinic of Soetomo General Hospital, Surabaya, Indonesia
Background Vulvovaginal Candidiasis (VVC) is one-third of vaginitis case. About 75% of women will have at least one episode of VVC. Complication of VVC can be unfavorable to impact the patient's quality of life. Knowing its risk factors can prevent someone suffering from pathological VVC and its sequelae. The purpose of this study was to identify risk factors of VVC. Materials and Methods A d...
متن کاملEtanercept in erythema nodosum leprosum*
One of the biggest challenges in treating leprosy is the control of reaction events. Patients with lepromatous leprosy may present reaction type II, or erythema nodosum leprosum, during treatment, and this reaction can remain in a recurrent form after being released from the hospital, requiring the use of thalidomide and/or prednisone for long periods of time, in turn increasing the risk of sid...
متن کاملMinocycline for Recurrent and/or Chronic Erythema Nodosum Leprosum.
Author Contributions:Drs Davis andMorr had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design:Davis, Sandroni. Acquisition, analysis, or interpretation of data:Davis, Morr, Warndahl. Drafting of the manuscript:Davis, Morr. Critical revision of the manuscript for important intellectual con...
متن کاملT-cell regulation in Erythema Nodosum Leprosum
Leprosy is a disease caused by Mycobacterium leprae where the clinical spectrum correlates with the patient immune response. Erythema Nodosum Leprosum (ENL) is an immune-mediated inflammatory complication, which causes significant morbidity in affected leprosy patients. The underlying cause of ENL is not conclusively known. However, immune-complexes and cell-mediated immunity have been suggeste...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmacognosy Journal
سال: 2023
ISSN: ['0975-3575']
DOI: https://doi.org/10.5530/pj.2022.14.165