Rifaximin versus Nonabsorbable Disaccharides for the Treatment of Hepatic Encephalopathy: A Meta-Analysis
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چکیده
منابع مشابه
Rifaximin versus Nonabsorbable Disaccharides for the Treatment of Hepatic Encephalopathy: A Meta-Analysis
Background. Many studies have found that the antibiotic rifaximin is effective for the treatment of hepatic encephalopathy. However, there is no uniform view on the efficacy and safety of rifaximin. Methods. We performed a meta-analysis through electronic searches to evaluate the efficacy and safety of rifaximin in comparison with nonabsorbable disaccharides. Results. A total of 8 randomized co...
متن کاملRifaximin versus nonabsorbable disaccharides in the management of hepatic encephalopathy: a meta-analysis.
OBJECTIVE To compare the positive and negative effects of rifaximin and nonabsorbable disaccharides in patients with hepatic encephalopathy. METHODS We used the method recommended by The Cochrane Collaboration to perform a meta-analysis of comparative randomized trials of rifaximin and nonabsorbable disaccharides. RESULTS Seven randomized controlled trials were identified, but only five tri...
متن کاملRifaximin treatment in hepatic encephalopathy.
BACKGROUND Hepatic encephalopathy is a chronically debilitating complication of hepatic cirrhosis. The efficacy of rifaximin, a minimally absorbed antibiotic, is well documented in the treatment of acute hepatic encephalopathy, but its efficacy for prevention of the disease has not been established. METHODS In this randomized, double-blind, placebo-controlled trial, we randomly assigned 299 p...
متن کاملRifaximin in the treatment of hepatic encephalopathy
Hepatic encephalopathy is a challenging complication in patients with advanced liver disease. It can be defined as a neuropsychiatric syndrome caused by portosystemic venous shunting, ranging from minimal to overt hepatic encephalopathy or coma. Its pathophysiology is still unclear, although increased levels of ammonia play a key role. Diagnosis of hepatic encephalopathy is currently based on s...
متن کاملrifaximin und Polyethylene Glycol as treatment Modalities in Hepatic Encephalopathy
Rifaximin is an antibiotic practically insoluble in water, hardly absorbable and only very little metabolized during intestinal transit. It has a broad spectrum of antibacterial efficacy and shows an excellent tolerability. Rifaximin decreased in clinical studies the plasma concentration of NH3, improved neurological symptoms, reduced the grade of severity of HE, and diminished the risk of bein...
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ژورنال
عنوان ژورنال: Gastroenterology Research and Practice
سال: 2013
ISSN: 1687-6121,1687-630X
DOI: 10.1155/2013/236963