منابع مشابه
Ribosome cycling
Eating Staph he scavenger receptor CD36 is required for binding and internalization of Staphylococcus aureus , report Stuart et al. (page 477). After recognizing lipoteichoic acid on the bacterial surface, CD36 teams up with toll-like receptors, TLR2/6, to trigger expression of pro-inflammatory cytokines. Researchers already knew that CD36 recognized apoptotic cells in both mammals and flies. I...
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Introduction This module is the seventh in a series of Extension materials designed to provide Extension agents, Certified Crop Advisers (CCAs), consultants, and producers with pertinent information on nutrient management issues. To make the learning ‘active,’ and to provide credits to CCAs, a quiz accompanies this module. In addition, realizing that there are many other good information source...
متن کاملConformational changes in switch I of EF-G drive its directional cycling on and off the ribosome.
We have trapped elongation factor G (EF-G) from Escherichia coli in six, functionally defined states, representing intermediates in its unidirectional catalytic cycle, which couples GTP hydrolysis to tRNA-mRNA translocation in the ribosome. By probing EF-G with trypsin in each state, we identified a substantial conformational change involving its conserved switch I (sw1) element, which contacts...
متن کاملRibosome structure
A ribosome is a vast assembly consisting of proteins and RNAs. The molecular mass adds up to approximately 2.5 MDa, and it is the largest asymmetric entity whose structure has been solved in human history. The first step of X-ray structure analysis is to acquire wellordered crystals of the target material. Generally speaking, crystallization becomes more difficult as the size of the molecule in...
متن کاملRibosome Rocks
If we are to talk about molecules of life, the ribosome, made of ribosomal RNA (rRNA) and protein, is a key: it stands at the junction between information and action, i.e. between nucleic acids and proteins. It is an extraordinarily sophisticated machine that takes the information present in mRNA and uses it to build proteins, containing over 250K atoms, and measuring more than 200 in every dir...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2005
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1703iti3