RhoA Controls Wnt Upregulation on Microstructured Titanium Surfaces
نویسندگان
چکیده
منابع مشابه
RhoA Controls Wnt Upregulation on Microstructured Titanium Surfaces
Rough topography enhances the activation of Wnt canonical signaling in vitro, and this mediates its effects on cell differentiation. However, the molecular mechanisms underlying topography-dependent control of Wnt signaling are still poorly understood. As the small GTPase RhoA controls cytoskeletal reorganization and actomyosin-induced tensional forces, we hypothesized that RhoA could affect th...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2014
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2014/401859