Rheumatoid factors specific for active rheumatoid arthritis.

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Rheumatoid factors specific for active rheumatoid arthritis.

To measure rheumatoid factors specific for patients with rheumatoid arthritis an enzyme linked immunosorbent assay (ELISA) was developed to measure rheumatoid factors in human serum that bind a cross-reactive determinant shared on human and other mammalian IgG. Rheumatoid factors that cross link human IgG and sheep IgG in a double binding ELISA were almost completely specific (greater than 99%)...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1990

ISSN: 0003-4967

DOI: 10.1136/ard.49.11.910