Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis
نویسندگان
چکیده
منابع مشابه
T-cell receptor biology and multiple sclerosis.
rat hippocampus depends on three kinds of excitatory amino acid receptors: quisqualate, kainate, and N-methy1-Daspartate (NMDA) receptors (see, e.g., [ 5 3 . Nevertheless, a common underlying mechanism could still be feasible, involvement of different transmitter systems notwithstanding. Indeed, D e Deyn and Macdonald [l] suggested the blocking of the GABA and glycine receptor-associated ion ch...
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Multiple sclerosis (MS) is a complex neurological disease and its prevalence is about 2 million in the world. Neuroinflammation plays a key role in MS. Vitamins are essential nutrients that have effective role on immune system including activation of lymphocyte and differentiation of T-helper cell. Vitamin D is a micronutrient that is effective on immune function. Deficiently of Vitamin D is a ...
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Multiple sclerosis (MS) is an inflammatory demyelinating disease where T cells attack the brain and the spinal cord. It is known that often particular T-cell clones are expanded in the target tissue, but it is still unknown, whether identical T-cell clones are present at distinct anatomical sites, or whether the T-cell spectrum is locally diverse. Therefore we compared the T-cell receptor (TCR)...
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12 چکیده تفاوت های فردی، به عنوان خصوصیات روانشناختی غالب، باید در سطوح مختلف تدریس و یادگیری زبان کاملاً مورد ملاحظه قرار گیرند. از میان تاثیرگذارترین سازه های روانشناختی که منجر به تفاوت های فردی می شوند، می توان ازهوش چندگانه و منبع کنترل نام برد. هوش چندگانه با جنبه های متفاوتی از هوش سر و کار دارد که ممکن است هر شخص از آن برخوردار باشد. منبع کنترل، به عنوان مفهوم روانشناختی دیگر، به استن...
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Background & Aims: 1,25-dihydroxyvitamin D3 (1,25 (OH)2 D3), the biologically active form of vitamin D, exerts an immunosuppressive effect through binding to its specific nuclear receptor. The present case-control study was done to examine the possible association of BsmI polymorphism in vitamin D receptor gene (VDR gene) with severity of multiple sclerosis (MS). Methods: 267 Iranian patients w...
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ژورنال
عنوان ژورنال: Genes & Immunity
سال: 2011
ISSN: 1466-4879,1476-5470
DOI: 10.1038/gene.2010.65