منابع مشابه
Revisiting the safety of aspartame.
Aspartame is a synthetic dipeptide artificial sweetener, frequently used in foods, medications, and beverages, notably carbonated and powdered soft drinks. Since 1981, when aspartame was first approved by the US Food and Drug Administration, researchers have debated both its recommended safe dosage (40 mg/kg/d) and its general safety to organ systems. This review examines papers published betwe...
متن کاملAspartame: review of safety.
Over 20 years have elapsed since aspartame was approved by regulatory agencies as a sweetener and flavor enhancer. The safety of aspartame and its metabolic constituents was established through extensive toxicology studies in laboratory animals, using much greater doses than people could possibly consume. Its safety was further confirmed through studies in several human subpopulations, includin...
متن کاملSafety of long-term large doses of aspartame.
Safety of long-term administration of 75 mg/kg of aspartame per day was evaluated with the use of a randomized, double-blind, placebo-controlled, parallel-group design in 108 male and female volunteers aged 18 to 62 years. Subjects received either aspartame or placebo in capsule form three times daily for 24 weeks. No persistent changes over time were noted in either group in vital signs; body ...
متن کاملOpinion of the Scientific Committee on Food: Update on the Safety of Aspartame
The Committee is asked to review all new scientific information on aspartame not having been examined by the SCF previously, taking into account, notably, the literature search carried out in the UK.
متن کاملRevisiting Safety and Liveness in the Context of Failures
Safety and liveness are two fundamental concepts for proving the correctness of concurrent programs. In the context of failures, however, we observe that some properties that are commonly believed to be safety properties are actually liveness properties. In this paper, we propose refinements of the concepts of safety and liveness that avoid this counterintuitive classification.
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ژورنال
عنوان ژورنال: Nutrition Reviews
سال: 2017
ISSN: 0029-6643,1753-4887
DOI: 10.1093/nutrit/nux035