Revisiting dandruff

Stratum corneum dysfunction in dandruff

Dandruff is characterized by a flaky, pruritic scalp and affects up to half the world's population post-puberty. The aetiology of dandruff is multifactorial, influenced by Malassezia, sebum production and individual susceptibility. The commensal yeast Malassezia is a strong contributory factor to dandruff formation, but the presence of Malassezia on healthy scalps indicates that Malassezia alon...

Evaluation of the clinical efficacy and safety of “Anti-Dandruff Shampoo” in the treatment of dandruff

Dandruff (Pityriasis simplex) is a common embarrassing scalp disorder, affecting a large chunk of population. The yeast, Pityrosporum ovale is the causative microorganism of dandruff and due to its lipase activity it releases proinflammatory free fatty acids, causing dermal inflammation and tissue damage. Currently available treatment options have various limitations, either due to poor clinica...

Seborrheic Dermatitis and Dandruff: A Comprehensive Review

Seborrheic Dermatitis (SD) and dandruff are of a continuous spectrum of the same disease that affects the seborrheic areas of the body. Dandruff is restricted to the scalp, and involves itchy, flaking skin without visible inflammation. SD can affect the scalp as well as other seborrheic areas, and involves itchy and flaking or scaling skin, inflammation and pruritus. Various intrinsic and envir...

Association of Malassezia species with dandruff

BACKGROUND & OBJECTIVES Malassezia species implicated with dandruff vary at different geographical locations. The present study was conducted to determine the spectrum and distribution of Malassezia species in dandruff patients and healthy individuals. METHODS Patients with dandruff from northern (Chandigarh) and southern (Manipal, Karnataka) parts of India (50 each) and healthy individuals (...

Dandruff and Seborrheic Dermatitis: A Head Scratcher