Revised UNAIDS/WHO Ethical Guidance for HIV Prevention Trials
نویسندگان
چکیده
Michael S. Saag, MD; Rajesh T. Gandhi, Jennifer F. Hoy, MBBS; Raphael J. Landovitz, Melanie A. Thompson, Paul E. Sax, Davey M. Smith, Constance Benson, Susan P. Buchbinder, Carlos del Rio, Joseph Eron Jr, Gerd Fätkenheuer, Huldrych Günthard, Jean-Michel Molina, Donna Jacobsen, BS; Volberding, MD
منابع مشابه
Ethics guidance for HIV prevention trials.
International trials of HIV prevention strategies are necessary to end the AIDS pandemic, but they present complex ethical challenges that are not uniformly or adequately addressed in existing guidance documents. The HIV Prevention Trials Network has developed ethics guidance that incorporates best practices and emerging consensus on four areas: x General principles x Meeting local needs and pr...
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The successful demonstration that antiretroviral (ARV) drugs can be used in diverse ways to reduce HIV acquisition or transmission risks--either taken as pre-exposure prophylaxis (PrEP) by those who are uninfected or as early treatment for prevention (T4P) by those living with HIV--expands the armamentarium of existing HIV prevention tools. These findings have implications for the design of fut...
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BACKGROUND This paper presents findings from a qualitative investigation of ethical and participatory issues related to the conduct of biomedical HIV prevention trials among marginalized populations in Thailand. This research was deemed important to conduct, as several large-scale biomedical HIV prevention trials among marginalized populations had closed prematurely in other countries, and a be...
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Although transgender women have been included in HIV prevention pre-exposure prophylaxis studies, no pre-exposure prophylaxis study has focused exclusively on transgender persons. Drawing on the cardinal principles of ethics espoused in the Belmont Report, this work highlights, among other issues, that (1) the principle of Justice requires the HIV prevention field to focus exclusively on transg...
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ژورنال
عنوان ژورنال: JAMA
سال: 2021
ISSN: ['0098-7484', '1538-3598']
DOI: https://doi.org/10.1001/jama.2021.0258