Review of Mass-Forming Intrahepatic Cholangiocarcinoma

The incidence of intrahepatic cholangiocarcinoma (iCCA) is highest in Eastern countries, such as Thailand, South Korea, and China, but its mortality are increasing worldwide. Over recent decades, the worldwide age-standardized for iCCA has been steadily increasing, whereas that perihilar CCA distal decreasing. macroscopic growth pattern somewhat different according to anatomic location tumor. can show three main patterns growth: mass forming, periductal infiltrating, intraductal growing. Morphologic classification important understand mode tumor spread, which critical predicting a tumor’s resectability planning extent surgery. Furthermore, types resulting imaging findings list differential diagnosis. This review provides comprehensive overview current knowledge what envisaged on horizon iCCA, focusing mas-forming type. 1. Tumor 2. Histological subtype 3. Imaging phenotype diagnosis 4. Staging 5. Preoperative prognostic prediction