Review of botulinum toxin type A for the prophylactic treatment of chronic daily headache

Review of botulinum toxin type A for the prophylactic treatment of chronic daily headache

Botulinum toxin A is increasingly used in the treatment of idiopathic and symptomatic headache disorders. However, only few controlled trials are available and many trials can hardly be compared to each other because of different endpoints and different trial designs. In particular chronic daily headache, which is defined as an idiopathic headache occurring on more than 15 days per month for at...

Botulinum toxin for treatment of primary chronic headache disorders.

Migraine. Since the 2002 TEC Assessment, 1 new study meeting selection criteria has appeared. Published in 2004 (n=60), this trial randomized patients to saline placebo, low-dose BTX-A, or high-dose BTX-A. No significant differences were reported at 3 months for any of 7 pain-related outcomes. The low dose of BTX-A had a lower rate of accompanying symptoms (photophobia, phonophobia, nausea and ...

Acupuncture and botulinum toxin A injection in the treatment of chronic migraine: A randomized controlled study

Background: Migraine is a common type of headache. Sometimes adequate pain relief is not achieved by conventional treatments. Acupuncture and botulinum toxin-A injection are known as non-pharmacological interventions for this purpose. The aim of this research was to compare the effect of acupuncture with botulinum toxin-A injection and pharmacological treatment in controlling chronic migraine. ...

Botulinum toxin type a as a prophylactic treatment for chronic daily headache: time to conduct a large clinical trial in Taiwan?

Common Prophylactic Practices for Chronic Daily Headache*

A variety of medications and treatment interventions, including antiepileptic drugs, tricyclic antidepressants, selective serotonin reuptake inhibitors, combined serotonin and norepinephrine reuptake inhibitors, β blockers, calcium channel antagonists, α2-adrenergic agonists, nonsteroidal anti-inflammatory drugs, muscle relaxants, occipital nerve blocks, and botulinum toxin type A injections, h...