Reversible Renal Failure in Malignant Hypertension

Microangiopathic hemolysis and renal failure in malignant hypertension.

Renal dysfunction is an important cause of morbidity and mortality in patients with malignant hypertension. Microangiopathic hemolysis (MAHA) related to malignant hypertension may cause renal insufficiency by obstruction of interlobular arteries. We hypothesized that the presence of MAHA is an important indicator of renal dysfunction and recovery in malignant hypertension. We retrospectively an...

Acute renal failure secondary to malignant hypertension induced thrombotic microangiopathy.

T thrombotic microangiopathy (TMA) represents a discreet group of disorders with common pathological features including fibrinoid necrosis, endothelial cell injury, and obstruction of vessels.1 The clinical presentation of TMA includes microangiopathic hemolytic anemia, thrombocytopenia, and functional impairment of various organ systems. Hemolytic uremic syndrome (HUS) and thrombotic thrombocy...

Hypertension and renal failure.

Long-term renal survival in malignant hypertension.

BACKGROUND Some studies have shown an improvement in the prognosis of patients with essential malignant hypertension (MHT), but data about long-term outcome and prognostic factors of these patients are scarce. METHODS We performed a single-centre retrospective analysis of 197 patients with MHT, diagnosed in the period 1974-2007. RESULTS Incidence of MHT remained stable along the different p...

Reversible Pulmonary Hypertension in an Infant Treated with Diazoxide

Background: Diazoxide is the main therapeutic agent for congenital hyperinsulinism. The drug is generally well tolerated; however, in this report severe adverse effects including heart failure (HF) and pulmonary hypertension (PH) in an infant are reported.Case report: A sixteen-day male infant with persistent hypoglycemia and with diagnosis of congenital hyperinsulinism underwent near total pan...