Reversible infertility in male mice after oral administration of alkylated imino sugars: A nonhormonal approach to male contraception
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چکیده
منابع مشابه
Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception.
During mammalian spermatogenesis, male germ cells undergo a dramatic transformation, which includes a change of shape, nuclear condensation, and development of specialised structures, such as an acrosome, and a flagellum with a mitochondrial sheath. We have found a previously undescribed pharmacological approach to intervene in these events. After oral administration of the alkylated imino suga...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.262586099