Reversal of rocuronium-induced (1.2 mg kg −1 ) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg −1 ) †
نویسندگان
چکیده
منابع مشابه
Drug Administration Hallucinogen Rating Scale Statistics Results 0.4-mg/kg Dose Perception Somaesthesia Affect Cognition Volition Intensity 0.2-mg/kg Dose 0.1-mg/kg Dose 0.05-mg/kg Dose Hallucinogen Rating Scale Technical Comment on Assessment of Subjective Effects Comment
SUBJECTS, MATERIALS, AND METHODS DRUG ADMINISTRATION HALLUCINOGEN RATING SCALE STATISTICS RESULTS 0.4-MG/KG DOSE PERCEPTION SOMAESTHESIA AFFECT COGNITION VOLITION INTENSITY 0.2-MG/KG DOSE 0.1-MG/KG DOSE 0.05-MG/KG DOSE HALLUCINOGEN RATING SCALE TECHNICAL COMMENT ON ASSESSMENT OF SUBJECTIVE EFFECTS COMMENT REFERENCES
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We have studied, in adult patients, ASA I-II, the cardiovascular effects of an intubating dose of rocuronium 0.6 mg kg-1. After induction, patients were paralysed with vecuronium and the trachea intubated. Heart rate (HR) and non-invasive mean arterial pressure (MAP) were measured every 1 min. After stabilization of HR and MAP, defined as < 3% change over three measurements, rocuronium (n = 20)...
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Five young adult Rhesus monkeys were included in this study. The weight of the animals ranged from 3.4 to 4.0 kg, with a mean of 3.6 kg. Each animal was restrained and anesthetized with ketamine HC1 at 25 mg/kg IM. An intravenous fluid of 5% dextrose and water with 1/4 normal saline was initiated and profused at a maintenance rate. Each monkey received intranasal midazolam (VersedTM, Roche Phar...
متن کاملCombined use of Sugammadex and Neostigmine for the Reversal of Rocuronium-Induced Profound Neuromuscular Blockade
Background: Sugammadex is a new reversal agent for nondepolarizing neuromuscular blockade. We conducted the randomized clinical study to compare the recovery between sugammadex alone and combined use of sugammadex and neostigmine. Methods: Forty adult patients were randomly allocated to Group S (n=20) or Group SN (n=20). General anesthesia was induced and maintained with propofol and remifentan...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2007
ISSN: 0007-0912
DOI: 10.1093/bja/aem057