Reversal of neutropenia with intravenous gammaglobulin in autoimmune neutropenia of infancy
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چکیده
منابع مشابه
Reversal of neutropenia with intravenous gammaglobulin in autoimmune neutropenia of infancy.
Intravenous gammaglobulin (IVIgG) was used to treat autoimmune neutropenia of infancy in two males with repeated infections. The neutrophil count increased significantly in both patients with the initial IVIgG therapy; 1 patient went into remission. The neutrophil count in the other remained above baseline for 3 wk, and a subsequent booster infusion also caused the neutrophil count to increase....
متن کاملAutoimmune neutropenia of infancy.
AIM Assessment of the clinical and haematological course of autoimmune neutropenia of infancy (ANI) in a defined childhood population in the south east of Scotland. METHODS From January 1986 to February 1991 all children presenting with persistent neutropenia were examined serologically for evidence of antigranulocyte antibodies. The clinical course of those children found to have anti-granul...
متن کاملAutoimmune neutropenia in early infancy: a review.
Fourteen infants with autoimmune neutropenia reported in the literature have been reviewed. Autoantibodies directed against their own neutrophils were demonstrated in the sera of these infants by agglutination, complement-dependent cytotoxicity, and immunofluorescence techniques. These antibodies were highly specific and were directed against antigens present on neutrophils. Among the currently...
متن کامل[Autoimmune neutropenia].
There have been several new developments in the field of autoimmune neutropenia over the past decade. Neutropenia caused by antibodies directed against granulocyte precursor cells, the oligoclonal nature of antineutrophil antibodies, and the expanding knowledge of neutrophil antigens, particularly in relationship to autoantibodies, are exciting new areas of investigation. Knowledge has also bee...
متن کاملAutoimmune neutropenia associated with autoimmune pancreatitis.
CONTEXT We report a rare case of autoimmune neutropenia associated with autoimmune pancreatitis. CASE REPORT A 61-year-old man was referred to our hospital with slight epigastralgia. He had been admitted to another hospital with exacerbation of diabetes and jaundice. Blood tests showed low white blood cell and neutrophil counts (1,800 µL-1 and 3%, respectively), and elevated transaminase, bil...
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ژورنال
عنوان ژورنال: Blood
سال: 1983
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v62.2.398.bloodjournal622398