Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development doi: 10.1242/dev.058479

Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium.

Cell polarity, mitotic spindle orientation and asymmetric division play a crucial role in the self-renewal/differentiation of epithelial cells, yet little is known about these processes and the molecular programs that control them in embryonic lung distal epithelium. Herein, we provide the first evidence that embryonic lung distal epithelium is polarized with characteristic perpendicular cell d...

Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development doi: 10.1242/dev.058479.

Publisher's Note: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium by El-Hashash et al. Development doi:10.1242/dev.058479.

Publisher's Note: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium by El-Hashash et al. Development This Publisher's Note relates to the article 'Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium' by El-Hashash et al. (doi:10.1242/dev.058479). We have recently bee...

Retraction: Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J. Cell. Sci. doi: 10.1242/102848.

The journal is retracting ‘Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium’ by Ahmed H. K. ElHashash, Gianluca Turcatel, Saaket Varma, Mohamed Berika, Denise Al Alam and David Warburton (2012). J. Cell Sci. 125, 4036-4048 (doi: 10.1242/102848). Journal of Cell Science is retracting this article at the request of the institution. The authors have been notifi...

Spindle orientation and asymmetric cell fate

Every organism begins as a single cell. Yet, in multicellular organisms, the progeny of that cell form a dazzling assortment of cell types. Generation of this diversity relies on asymmetric divisions. In contrast with symmetric divisions, which faithfully duplicate the characteristics of the parent cell, asymmetric divisions create two daughters that have different fates or identities. Asymmetr...