Retinopathy and the association with pegylated interferon and Ribavirin

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[Pegylated interferon and ribavirin associated retinopathy in patients with hepatitis C].

CASE REPORT We describe two patients with chronic hepatitis C, treated with pegylated interferon and ribavirin, who developed multiple cotton-wool spots in the retina of both eyes. The ocular findings were identified as pegylated interferon associated retinopathy, and in one case spontaneously resolved and in the other after the treatment was withdrawn. DISCUSSION Interferon is an immunomodul...

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Pegylated interferon and ribavirin in haemodialysis patients.

Scr and LM, that can be correctly assessed in renal insufficient patients without DEXA, simply from anthropometrics or body impedance analysis [3], would constitute important progress for practice. However, the relationships between LM and creatinine production, and between Scr and glomerular filtration, are not simple. The formula proposed by Taylor et al. [1] leads to an important overestimat...

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Pegylated interferon and ribavirin-induced interstitial pneumonitis with ARDS.

A 49-year-old man with cirrhosis due to hepatitis C virus developed interstitial pneumonitis documented by surgical lung biopsy specimen evaluation after two weekly doses of pegylated interferon-alpha(2)b in combination with ribavirin. He developed ARDS and died after 26 days of hospitalization from multisystem organ failure. This case suggests that interstitial pulmonary disease can occur with...

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Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy

Hepatitis C virus infection is the leading cause of chronic liver disease in the United States of America. Pegylated interferon α and ribavirin combination is the mainstay of treatment. Severe pulmonary toxicities are rarely reported. We report here a case of severe form of organizing pneumonia secondary to pegylated interferon α therapy presenting as acute respiratory failure. Patient has near...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2012

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2012.05.194