Retinoic acid stability in stem cell cultures

P-92: Retinoic Acid and STO Co-Culture System Enhance Mouse Embryonic Stem Cell

The Effect of Retinoic Acid on Seminal Vesicle Epithelial Cell

Purpose: The seminal vesicles are androgen dependent exocrine glands producing protein-rich secretion. The retinoic acid has been implicated as a signaling molecule for the seminal vesicle development. In the present study, the effect of retinoic acid on seminal vesicle epithelial cell of neonatal mouse was investigated. Materials and Methods: Newborn male N-MRI mice were injected intraperiton...

Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell Formation

Hematopoietic stem cells (HSCs) are multipotent progenitors that generate all vertebrate adult blood lineages. Recent analyses have highlighted the importance of somite-derived signaling factors in regulating HSC specification and emergence from dorsal aorta hemogenic endothelium. However, these factors remain largely uncharacterized. We provide evidence that the vitamin A derivative retinoic a...

Analysis of Promyelocytic Leukemia in Human Embryonic Carcinoma Stem Cells During Retinoic Acid-Induced Neural Differentiation

Background: Promyelocytic leukemia protein (PML) is a tumor suppressor protein that is involved in myeloid cell differentiation in response to retinoic acid (RA). In addition, RA acts as a natural morphogen in neural development. Objectives: This study aimed to examine PML gene expression in different stages of in vitro neural differentiation of NT2 cells, and to investigate the possible role o...

Fish Stem Cell Cultures

Stem cells have the potential for self-renewal and differentiation. First stem cell cultures were derived 30 years ago from early developing mouse embryos. These are pluripotent embryonic stem (ES) cells. Efforts towards ES cell derivation have been attempted in other mammalian and non-mammalian species. Work with stem cell culture in fish started 20 years ago. Laboratory fish species, in parti...