Retinal ganglion cells: Development, function, and disease

Retinal ganglion cells: Development, function, and disease

Thirteenth Annual Vision Research Conference April 30–May 1–2, 2010 Convention Center Ft. Lauderdale, FL The 13th Annual Vision Research Conference, ‘‘Retinal ganglion cells: development, function, and disease’’ was held at the Convention Center at Ft. Lauderdale, Florida, April 30–May 1, 2010. The meeting was very well attended (294 registrations), and 39 invited speakers reviewed the latest d...

Retinal Ganglion Cell Complex in Alzheimer Disease: Comparing Ganglion Cell Complex and Central Macular Thickness in Alzheimer Disease and Healthy Subjects Using Spectral Domain-Optical Coherence Tomography

Introduction: Alzheimer disease (AD) is the most common form of dementia worldwide. The modalities to diagnose AD are generally expensive and limited. Both the central nervous system (CNS) and the retina are derived from the cranial neural crest; therefore, changes in retinal layers may reflect changes in the CNS tissue. Optical coherence tomography (OCT) machine can show delicate retinal layer...

Physiologic Diversity and Development of Intrinsically Photosensitive Retinal Ganglion Cells

Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate numerous nonvisual phenomena, including entrainment of the circadian clock to light-dark cycles, pupillary light responsiveness, and light-regulated hormone release. We have applied multielectrode array recording to characterize murine ipRGCs. We find that all ipRGC photosensitivity is melanopsin dependent. At least three popu...

Retinal Ganglion Cells

Segments from adult fish and rat retinae were explanted on myelinmarker expressing oligodendrocytes derived from the regenerating goldfish optic nerve. Fish axons grew in high density and even rat retinal axons regenerated to considerable length on the surface of the fish oligodendrocytes, suggesting that this type of fish glia has axon-growth promoting surface components that exert their influ...

Retinal Ganglion Cells