Reshaping a therapeutic CD4 antibody.
نویسندگان
چکیده
منابع مشابه
Reshaping Antibody Diversity
Some species mount a robust antibody response despite having limited genome-encoded combinatorial diversity potential. Cows are unusual in having exceptionally long CDR H3 loops and few V regions, but the mechanism for creating diversity is not understood. Deep sequencing reveals that ultralong CDR H3s contain a remarkable complexity of cysteines, suggesting that disulfide-bonded minidomains ma...
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A mesiodens is a supernumerary tooth that is found in the midline of the maxilla. Fifteen percent erupt usually between the ages of 3 and 7. The standard treatment is extraction of the supernumerary to allow the permanent incisors to erupt properly. This case report describes an instance where the primary incisor was prematurely exfoliated due to the eruption of the mesiodens. Because of the fa...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1991
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.88.10.4181