Research Progress in Focal Treatment of Prostate Cancer

Focal therapy for prostate cancer. Alternative treatment.

CONTEXT The great controversy surrounding the treatment of localized prostate cancer is related with its possibilities of radical treatment or active surveillance. The objective of this paper is to analyze the rationale selection among current focal therapy modalities regarding tumor and patient selection. EVIDENCE ACQUISITION Current articles about advantages and disadvantages on the treatme...

Focal cryotherapy in the treatment of localized prostate cancer.

BACKGROUND The management choice for newly diagnosed localized prostate cancer presents a challenge to both the physician and the patient. Traditionally, surgery and radiation therapy have been the most commonly recommended options. More recently, active surveillance is recommended as the preferred management choice for a subset of men with localized, low-risk cancer. Recent reports also sugges...

Progress in prostate cancer.

Progress in the treatment of advanced prostate cancer.

The androgen receptor (AR) is the most significant target for patients with metastatic castration-resistant prostate cancer (mCRPC). There is now irrefutable evidence that the AR axis is functional in most patients throughout the history of prostate cancer, is crucial from diagnosis to death, even in patients who have received hormonal manipulation, and represents a relevant therapeutic target ...

Advances in Prostate Cancer Research and Treatment

1 Radiotherapy Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Largo Brambilla 3, 50134 Firenze, Italy 2 Department of Experimental Medicine, Sapienza University, 00161 Rome, Italy 3 RestorGenex Pharmaceuticals, Inc., 37 Neillian Crescent, Jamaica Plain, MA 02130, USA 4Laboratory of Radiobiology and Division of Radiotherapy, Department of Applied, Clin...