Reproductive Dysfunction in Female Rats With Renovascular Hypertension
نویسندگان
چکیده
منابع مشابه
Reproductive dysfunction in female rats with renovascular hypertension.
BACKGROUND Hypertension is a major public health epidemic that is highly associated with sexual dysfunction in both men and women. Despite its high prevalence, clinical and animal literature on the underlying mechanisms of sexual dysfunction in hypertensive women is remarkably limited. METHODS Using a well-established rodent model of renovascular hypertension-the 2-kidney, 1-clip (2K1C) Goldb...
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To test whether hypertension can cause hyperinsulinemia or insulin resistance, we performed intravenous glucose tolerance tests at 1 month and euglycemic clamps at 3 months after induction of two-kidney, one clip renovascular hypertension in rats. At 1 month, systolic pressure was higher in 21 clipped than in 12 control animals (161 +/- 5 mm Hg, range 134-187 mm Hg versus 119 +/- 3 mm Hg, range...
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There is an association between hypertension and reproductive dysfunction. Angiotensin II (Ang II) is involved in the pathogenesis of hypertension and the regulation of reproduction. The present study aimed to determine whether the angiotensinergic system mediates the effects of hypertension on reproductive function in male rats subjected to a two-kidney, one-clip (2K1C) model. Sexual behavior ...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2012
ISSN: 0895-7061,1941-7225
DOI: 10.1093/ajh/hps026