Reproductive Benefit of Oxidative Damage: An Oxidative Stress “Malevolence”?
نویسندگان
چکیده
منابع مشابه
Reproductive Benefit of Oxidative Damage: An Oxidative Stress “Malevolence”?
High levels of reactive oxygen species (ROS) compared to antioxidant defenses are considered to play a major role in diverse chronic age-related diseases and aging. Here we present an attempt to synthesize information about proximate oxidative processes in aging (relevant to free radical or oxidative damage hypotheses of aging) with an evolutionary scenario (credited here to Dawkins hypotheses)...
متن کاملFree Radicals, Oxidative Stress and Oxidative Damage in Parkinson's Disease
Parkinson’s disease (PD) is an adult-onset disease of unknown etiology, with a prevalence of 0.3% in the entire population, affecting more than 1% of humans over 60 years of age. Primary degeneration occurs in pigmented dopamine-containing neurons in the pars compacta of the substantia nigra, with projections to the striatum and typical motor signs that appear with a loss of 60% of the dopamine...
متن کاملOxidative Stress on Male Reproductive Toxicity
Globally Harmonized System defines Reproductive Toxicity as “an adverse effects (of chemicals) on sexual function and fertility in adult males and females, as well as developmental toxicity in the offspring.” Several toxicity assessment studies have been performed taking into account the action of toxicants on reproductive activity. Testis is the main organ of male reproductive system and sperm...
متن کاملOxidative stress and male reproductive health
One of the major causes of defective sperm function is oxidative stress, which not only disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a result of collateral damage to proteins and lipids in the sperm plasma membrane. The origins of such oxidative stress appear to involve the sperm mitochondria, which have a tendency to generate high levels of su...
متن کاملOxidative stress in an assisted reproductive techniques setting.
OBJECTIVE The manipulation of gametes and embryos in an in vitro environment when performing assisted reproductive techniques (ART) carries the risk of exposure of these cells to supraphysiological levels of reactive oxygen species (ROS). The main objective of this review is to provide ART personnel with all the necessary information regarding the development of oxidative stress in an ART setti...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2011
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2011/760978