Reply to Liu et al.: Haplotype matters: CD226 polymorphism as a potential trigger for impaired immune regulation in multiple sclerosis
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چکیده
منابع مشابه
Reply to Murrell et al.: Noise matters.
The concept of statistical " equitability " plays a central role in the 2011 paper by Reshef et al. (1). Formalizing equitability first requires formalizing the notion of a " noisy functional relationship, " that is, a relationship between two real variables, X and Y, having the form Y = f ðXÞ + η; where f is a function and η is a noise term. Whether a dependence measure satisfies equi-tability...
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In a letter to the editor, Liu et al. (1) find that PTEN contains some transcript variants that are polyadenylated and prematurely terminated in the first intron of PTEN. These transcripts are suggested to be 5′-UTR– containing promoter-spanning and to encode for three small RNAs (sRNAs), with one of these (sRNA3) being antisense to oligodeoxynucleotide 2 (ODN2), which was one of two ODNs used ...
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We thank Liu et al. (1) for their comments on our work on the link between the cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)-related protease high temperature requirement protein A1 (HtrA1) and the TGF-β signaling pathway. To advance our understanding of the mechanisms underlying HtrA1 deficiency, we used dermal fibroblasts from CARASIL pa...
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We thank Liu et al. (1) for their comments on our manuscript in which hepatocyte nuclear factor 4 alpha (HNF4A) and polypyrimidine tract binding protein 1 (PTBP1) are identified as potential dynamic biomarkers for Parkinson’s disease (PD) (2). In our study, transcriptomic and network-based metaanalysis identified HNF4A and PTBP1 as the most significant up-regulated and down-regulated genes, res...
متن کاملReply to Gratiy et al.
TO THE EDITOR: Gratiy et al. (2013) proposed two alternative explanations for the nonbalanced current source density (CSD) estimates in Riera et al. (2012). Their commentary was based on a particular interpretation of the role played by the Ampere-Maxwell Law in the genesis of the electric fields for macroscopic media. In this Reply, we will provide further information to stimulate the debate i...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2017
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1619059114