Reply to Dr. Philip Murphy

Reply to Dr. Weiskirchen.

TO THE EDITOR: We would like to thank Dr. Weiskirchen (5) for his interest in our recent publication (3). As we mentioned in the DISCUSSION and as pointed out by Dr. Weiskirchen, the absence of protein data in our adenovirus model represents a limitation of our study. Regarding the RNA expression, we also expected to find a greater difference in ccn1/cyr61 gene expression in the mice instilled ...

Reply to Dr. Chacko.

TO THE EDITOR: We thank Dr. Chacko (2) for reading our recently published article (3) and providing comments. In her first point, she makes the argument that moderate intensity exercise 45 min after a meal improves postprandial glycemia more effectively compared with higher intensity exercise. This statement was made based on findings from three different studies consisting of three different p...

Reply to Dr. Yamamoto's letter.

We wish to thank Dr. Yamamoto for his letter,1 regarding our paper ‘Exclusive elemental diet impacts on the gastrointestinal microbiota and improves symptoms in patients with chronic pouchitis’.2 In his letter Dr. Yamamoto outlines the changes in cytokines that his group have identified in patients treated with elemental diet for Crohn's disease who experienced symptomatic benefit with this tre...

Reply to Dr. Kotze's and Dr. Yamamoto's letter.

We appreciate the opportunity to reply to Dr. Kotze's and Dr. Yamamoto's letter1 about our paper “Prevention of postoperative recurrence with azathioprine or infliximab in patients with Crohn's disease: an open-label pilot study”, recently accepted for publication in JCC.2 We agree with the first comment concerning the hypothesis that the use of anti-TNF (tumor necrosis factor)-α before surgery...

Dr. Wallace and Dr. Stone reply.