Reply: environmental estrogens and sperm function
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Topic 3.16 Environmental estrogens and sperm counts*
The term “environmental estrogen” refers to chemical substances that exhibit some degree of estrogen-like activity. The primary emphasis for potential adverse effects resulting from exposure to environmental estrogens is on in utero exposure because such exposure can occur during critical periods of organogenesis. Assessment of biological plausibility can be based, in part, on the extensive dat...
متن کاملEnvironmental Estrogens
John A. McLachlan and Steven F. Arnold n many ways, the story of the pesticide DDT is the story of America's attitude toward synthetic chemicals in the environment. DDT was the first of many new pesticides that people hoped would improve the quality of their lives, but gradually it became clear that such progress often had a cost. DDT was one of the first environmental chemical agents to*be ban...
متن کاملEnvironmental estrogens.
The estrogenic equivalent analysis that Dr. Safe presented recently in EHP (103:346-351) is a welcome addition to the literature , and development of this toxicologic approach is an important step in evaluating new endpoints for environmental agents (1,2). The hormonal potential of chemical contaminants offers many opportunities for further research, including study of the environmental etiolog...
متن کاملEstrogens and brain function.
Cognitive decline is well recognized during ageing but is often accelerated in women after menopause. Studies have shown that there are significant gender differences in brain ageing with significantly greater changes in brain structure, function and metabolism between females and males. Estrogens exert protective effects on neuronal cells in culture but the exact underlying mechanism for their...
متن کاملEstrogens and epididymal function.
Estrogen is synthesized in the male reproductive system and is found in high concentrations in rete testis and seminal fluids. This luminal estrogen targets estrogen receptors (ER) along the male reproductive tract, and in particular the efferent ductules, where ERalpha is abundant. However, both ERalpha and ERbeta are found in various regions of the male reproductive tract. The transgenic ER k...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2004
ISSN: 1460-2350
DOI: 10.1093/humrep/deh016