Repeated stunning precedes myocardial hibernation in progressive multiple coronary artery obstruction

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Repeated stunning precedes myocardial hibernation in progressive multiple coronary artery obstruction.

OBJECTIVE The aim of this study was to characterize a regional myocardial flow-function relationship in collateral dependent myocardium produced by multiple coronary artery obstruction. METHODS Ameroid constrictors were placed around the proximal right (RC) and circumflex (CX) coronary arteries and a silicon tubing cuff around the proximal LAD (left anterior descending artery) (luminal stenos...

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Stunning, hibernation, and assessment of myocardial viability.

The last 3 decades have witnessed an unprecedented improvement in the outcome of patients with acute coronary syndromes. The widespread use of thrombolytic therapy and percutaneous coronary interventions, in association with increasingly potent antithrombotic agents, has contributed to significant reductions in mortality and morbidity in these patients. Although overall survival has improved, a...

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Myocardial hibernation and stunning: from physiological principles to clinical practice.

In patients with coronary artery disease, one of the most powerful determinants of prognosis is left ventricular function. 2 Thus, if we assume that the prognostic benefit of revascularisation is mediated through an eVect on left ventricular function, two mechanisms might explain this benefit. First, coronary artery bypass surgery or angioplasty could reduce the impact of coronary artery diseas...

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Postischemic myocardial stunning is superior to transient ischemic dilation for detecting multivessel coronary artery disease.

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1999

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(99)00467-2