Renin-angiotensin-aldosterone system in cirrhosis.
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چکیده
منابع مشابه
Renin-angiotensin-aldosterone system in cirrhosis.
According to traditional concepts, ascites formation and portal hypertension in cirrhosis lead to a deficit in the 'effective' extracellular fluid (ECF) and blood volumes respectively. The renin-angiotensin-aldosterone (RAA) system is thus stimulated and the kidneys retain fluid as a homeostatic mechanism to restore the ECF and blood volumes. Recent studies, however, show that approximately two...
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Chronic heart failure (CHF) is associated with endothelial dysfunction. Activation of the renin-angiotensin-aldosterone system (RAAS) is believed to be important in the deterioration of endothelial dysfunction in CHF through stimulation of oxidative stress. Whereas angiotensin-converting enzyme inhibitors (ACE-I) improve endothelial function in CHF, the effects of angiotensin II AT 1-receptor b...
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Circulation Research is available at http://circres.ahajournals.org DOI: 10.1161/CIRCRESAHA.116.303587 Abstract: Blockers of the renin–angiotensin–aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the treatment of hypertension. How exactl...
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ژورنال
عنوان ژورنال: Gut
سال: 1980
ISSN: 0017-5749
DOI: 10.1136/gut.21.6.545