منابع مشابه
Renal protection in cardiovascular surgery
Acute kidney injury (AKI) is one of the most relevant complications after major surgery and is a predictor of mortality. In Western countries, patients at risk of developing AKI are mainly those undergoing cardiovascular surgical procedures. In this category of patients, AKI depends on a multifactorial etiology, including low ejection fraction, use of contrast media, hemodynamic instability, ca...
متن کاملRenal protection in cardiovascular surgery [version 1; referees: 2 approved]
Acute kidney injury (AKI) is one of the most relevant complications after major surgery and is a predictor of mortality. In Western countries, patients at risk of developing AKI are mainly those undergoing cardiovascular surgical procedures. In this category of patients, AKI depends on a multifactorial etiology, including low ejection fraction, use of contrast media, hemodynamic instability, ca...
متن کاملARBs for cardiovascular and renal protection in high-risk patients.
The contribution of recent trials such as the extensive ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial) ‘a thorough, double-blind, prospective, randomised trial, which documents the equal-outcome efficacy of an ARB (telmisartan) and an ACE inhibitor in a high-risk population’ is noted in a recent meta-analysis of ARBs. Among ARBs, telmisartan is furth...
متن کاملPerfusion techniques for renal protection during thoracoabdominal aortic surgery.
Open thoracoabdominal aortic aneurysm (TAAA) repair includes aortic clamping that interrupts antegrade blood flow to distal organs. Ischemia involving the kidneys can lead to renal failure and poor outcomes. To this end, prevention of ischemic kidney damage has led to several perfusion strategies that protect the kidneys during TAAA surgery. Options for renal perfusion include the use of passiv...
متن کاملEplerenone: cardiovascular protection.
Data from animal studies and clinical trials indicate that aldosterone causes cardiovascular and renal injury through mineralocorticoid receptor-dependent mechanisms. However, although aldosterone receptor antagonism reduces mortality in patients with congestive heart failure, the progestational and antiandrogenic side effects of the nonspecific aldosterone receptor antagonist, spironolactone, ...
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ژورنال
عنوان ژورنال: F1000Research
سال: 2016
ISSN: 2046-1402
DOI: 10.12688/f1000research.7348.1