منابع مشابه
Genetic diseases of renal phosphate handling.
UNLABELLED Renal control of systemic phosphate homeostasis is critical as evident from inborn and acquired diseases causing renal phosphate wasting. At least three transport proteins are responsible for renal phosphate reabsorption: NAPI-IIa (SLC34A1), NAPI-IIc (SLC34A3) and PIT-2 (SLC20A2). These transporters are highly regulated by various cellular mechanisms and factors including acid-base s...
متن کاملRole of aquaporins in renal water handling: physiology and pathophysiology.
the six bilayer spanning domains are connected by five Introduction loops (A–E in Figure 1). The molecule consists of two repeats of three a-helices which are 180° mirror images An essential function of the mammalian kidney is its of each other (Figure 1). Each repeat contains the ability to conserve or excrete free water independent highly conserved family characteristic asparagineof changes i...
متن کاملFGF-23: More Than a Regulator of Renal Phosphate Handling?
Fibroblast growth factor 23 (FGF-23) is likely to be the most important regulator of phosphate homeostasis, which mediates its functions through FGF receptors and the coreceptor Klotho. Besides reducing expression of the sodium-phosphate cotransporters NPT2a and NPT2c in the proximal tubules, FGF-23 inhibits the renal 1α-hydroxylase and stimulates the 24-hydroxylase, and it appears to reduce pa...
متن کاملFull Review Genetic diseases of renal phosphate handling
UNLABELLED: Renal control of systemic phosphate homeostasis is critical as evident from inborn and acquired diseases causing renal phosphate wasting. At least three transport proteins are responsible for renal phosphate reabsorption: NAPI-IIa (SLC34A1), NAPI-IIc (SLC34A3) and PIT-2 (SLC20A2). These transporters are highly regulated by various cellular mechanisms and factors including acid-base ...
متن کاملEffect of fasting on renal physiology
Total abstention from food and water from sunrise to sunset during the month of Ramadan, is practiced by hundreds of millions of Muslims throughout the world. This pattern of fasting during Ramadan is different from the usual fasting as people are allowed to eat and drink between sunset and dawn but not after dawn. The amount and type of food (rich in protein, fat and sugar) eaten during the n...
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ژورنال
عنوان ژورنال: Indian Journal of Endocrinology and Metabolism
سال: 2013
ISSN: 2230-8210
DOI: 10.4103/2230-8210.113752